Megakaryocyte Platelet Synopsis

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cell type Internal Number subtype transcriptome proteome literature Title Publish date Additional Data
Platelet 113 Megakaryocyte x
Macaulay et al. Blood Macaulay et al. Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. Blood. 2007 Apr 15;109(8):3260-9. Epub 2006 Dec 27. 2007-04 http://bloodjournal.hematologylibrary.org/cgi/content/full/blood-2006-07-036269/DC1
Megakaryocyte 116
x
Raslova et al. Blood Raslova et al. Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach. Blood. 2007 Apr 15;109(8):3225-34. Epub 2006 Dec 14. 2007-04 http://bloodjournal.hematologylibrary.org/cgi/content/full/blood-2006-07-037838/DC1

16
x
Mi-Hyun Shim et al. Puget Sound Blood Center Gene expression profile of primary human CD34 CD38lo cells differentiating along the megakaryocyte lineage - Experimental Hematology 32 (April 2004) 638–648 2004-04 no Further Data

10
x
Judith A. Coppinger et al. Blood Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions, 2004 103: 2096-2104 Prepublished online Nov 20, 2003; doi:10.1182/blood-2003-08-2804 2003-11 http://bloodjournal.hematologylibrary.org/cgi/content/full/2003-08-2804/DC1

24
x
Hyung-Lae Kim, Experimental and Molecular Medicine Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells 2003-10 no Further Data

20
x
Peter Bugert el al. , Thromb Haemost Messenger RNA profiling of human platelets by microarray hybridization, Thromb Haemost 2003; 90: 738–48 2003-02 no Further Data

15
x
Jeong-Ah Kim et al., STEM CELLS Gene Expression Profile of Megakaryocytes from Human Cord Blood CD34+ Cells Ex Vivo Expanded by Thrombopoietin Stem Cells 2002;20;402-416 2002-12 no Further Data

14

x Aaron Tomer, Blood Human marrow megakaryocyte differentiation: multiparameter correlative analysis identifies vonWillebrand factor as a sensitive and distinctive marker for early (2N and 4N) megakaryocytes, Prepublished online Jun 15, 2004; 2004 104: 2722-2727, doi:10.1182/blood-2004-02-0769 2004-06 no Further Data

13

x Els den Dekker, BBA Cell-to-cell variability in the differentiation program of human megakaryocytes - Biochimica et Biophysica Acta 1643 (2003) 85– 94 2003-09 no Further Data

104

x Christine LACABARATZ-PORRETT et al. Biogenesis of endoplasmic reticulum proteins involved in Ca2+ signalling during megakaryocytic differentiation: an in vitro study, Biochem. J (2000) 350, 723-734 2000-00 no Further Data

114 Platelet x
Jones et al. J Thromb Haemost Jones et al. Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus. J Thromb Haemost. 2007 Aug;5(8):1756-65. 2007-08 dead Link

115
x
Raghavachari et al. Circulation Raghavachari et al. Amplified expression profiling of platelet transcriptome reveals changes in arginine metabolic pathways in patients with sickle cell disease. Circulation. 2007 Mar 27;115(12):1551-62. Epub 2007 Mar 12. 2007-03 http://circ.ahajournals.org/cgi/content/full/CIRCULATIONAHA.106.658641/DC1

118
x
Bugert et al. Platelets Bugert et al. Profiling of gene transcripts in human platelets: an update of the platelet transcriptome. Platelets. 2006 Nov;17(7):503-4. 2006-11 no Further Data

112
x
Healy et al. Circulation Healy et al. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation. 2006 May 16;113(19):2278-84. Epub 2006 May 8. 2006-05 http://circ.ahajournals.org/cgi/content/full/CIRCULATIONAHA.105.607333/DC1

122
x
Macaulay et al. Clinical Investigation Macaulay et al. Platelet genomics and proteomics in human health and disease. Clinical Investigation. 2005 Dec;115(12):3370-3377 2005-12 no Further Data

100
x
Jutta Maria Rox et al. , Clinical Chemistry Gene Expression Analysis in Platelets from a Single Donor: Evaluation of a PCR-Based Amplification Technique, Clinical Chemistry 50:12 2271-2278 (2004) 2004-00 http://www.clinchem.org/cgi/content/full/clinchem.2004.035386/DC1

8
x
Dmitri Gnatenko et al., Blood Gnatenko et al. Transcript profiling of human platelets using microarray and serial analysis of gene expression. Blood. 2003 Mar 15;101(6):2285-93. Epub 2002 Nov 14. 2003-03 no Further Data

119

x Guerrier et al. J Proteome Res. Guerrier et al. Exploring the platelet proteome via combinatorial, hexapeptide ligand libraries. J Proteome Res. 2007 Nov;6(11):4290-303. Epub 2007 Oct 6. 2007-10 paper damaged

111

x Maynard et al. J Thromb Haemost Maynard et al. Proteomic analysis of platelet alpha-granules using mass spectrometry. J Thromb Haemost. 2007 Sep;5(9):1945-55. 2007-09 no Further Data

120

x Walowiak et al. Platelats Walkowiak et al. The blood platelet proteome is changed in UREMIC patients. Platelets. 2007 Aug;18(5):386-8. 2007-08 no Further Data

110

x Martens et al. Proteomics Martens et al. The human platelet proteome mapped by peptide-centric proteomics: a functional protein profile. Proteomics. 2005 Aug;5(12):3193-204. 2005-08 stored locally

117

x Tyan et al. J Biomed Mater Res A Tyan et al. Proteomic profiling of platelet proteins by trypsin immobilized self-assembled monolayers digestion chip and protein identification using electrospray ionization tandem mass spectrometry. J Biomed Mater Res A. 2004 Oct 1;71(1):90-7. 2004-10 no Further Data

9

x Maguire et al. Pathophysiol Thromb Platelet Proteomics: Identification of Potential Therapeutic TargetsPathophysiol Haemost Thromb 2003/2004; 33: 481-486 2004-00 no Further Data

103

x McRedmond et al. MCP papers Integration of Proteomics and Genomics in Platelets - A PROFILE OF PLATELET PROTEINS AND PLATELET-SPECIFIC GENES, MCP Papers in Press, November 25, 2003, DOI 10.1074/mcp.M300063-MCP200 2003-11 http://www.mcponline.org/cgi/content/full/M300063-MCP200/DC1

10

x Judith A. Coppinger et al. Blood Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions, 2004 103: 2096-2104 Prepublished online Nov 20, 2003; doi:10.1182/blood-2003-08-2804 2003-11 http://bloodjournal.hematologylibrary.org/cgi/content/full/2003-08-2804/DC1

11

x Garcia et al. Blood Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins, 2004 103: 2088-2095, doi:10.1182/blood-2003-07-2392 Prepublished online Nov 26, 2003; 2003-11 no Further Data

101

x Flaumenhaft el al. Chemistry and Biology, Vol 10 The platelet as a Model for Chemical Genetics, Chemistry & Biology, Vol 10, 481-486, DOI 10.1016/S1074-5521(03)00127-3 2003-06 no Further Data

22

x Maguire et al. , Journal of Thrombosis and Haemostasis Platelet Proteomics, Journal of Thrombosis and Haemostasis, 1:1593-1601 2003-00 no Further Data

23

x Maguire et al., Proteomics Identification of the phosphotyrosine proteome from thrombin activated platelets, Proteomics 2002,2, 642-648 2002-00 dead Link

25

x O´Neill et al., Proteomics Towards complete analysis of the platelet proteome, Proteomics 2002,2,288-305 2002-00 no Further Data

102

x Marcus Katrin et al. Electrophoresis Identification of platelet proteins separated by two-dimensional gel electrophoresis and analyzed ty matrix assisted laser desorption/ionization-time of flight-mass spectrometry and detection of tyrosine-phosphorylated proteins, Electrophoresis 2000, 21, 2622-2636 2000-00 no Further Data

121 Platelet Microparticles
x Garcia et al. J Proteome Res Garcia et al. The platelet microparticle proteome. J Proteome Res. 2005 Sep-Oct;4(5):1516-21. 2004-09 no Further Data
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