P06 ETHZ

Email: Christian Wolfrum

a systems biology approach. The mission of the Institute is to develop, apply and teach the emerging science of Systems Biology. We understand Systems Biology as an approach to biological research that studies biological systems and processes as dynamic, integrated networks of interacting molecules. The underlying vision is that the structure and dynamics of such networks will provide insights into the function and control of biological systems that are not apparent from studying the systems’s components. Complex metabolic disorders such as obesity, diabetes and cancer are considered major health risks globally. With the completion of the sequencing of the genomes of several species including humans the challenge is now to systematically decipher and integrate the many different levels of biological information and to apply this newly gained knowledge towards a better understanding of these complex diseases. The available technologies include high throughput genotyping platforms and DNA-arrays for genetic analysis, protein analysis by MALDI-TOF. Furthermore, RNAi imagebased high throughput screening is available for high-content screening applications such